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EcoR1 Capital, LLC

hedge fundUpdated 27 days ago

Managed by Ecor1 Capital, Llc • Latest filing Q2 2026

Portfolio value
$2.1B
Q2 2026
Filings
14
Quarterly 13F history
Top-10 concentration
98.1%
Weight of largest holdings
Annualized return
-8.8%
Implied from 13F holdings

Portfolio value history

13F-disclosed portfolio value over 14 quarters

Show data table
PeriodPortfolio value
Q1 2023$3.1B
Q2 2023$4.1B
Q3 2023$3B
Q4 2023$3.9B
Q1 2024$4B
Q2 2024$3.3B
Q3 2024$2.9B
Q4 2024$2.6B
Q1 2025$1.7B
Q2 2025$1.7B
Q3 2025$2.1B
Q4 2025$2.2B
Q1 2026$2.4B
Q2 2026$2.1B

Top holdings

33 positions as of Q2 2026

View filing
Z

ZYMEWORKS INC

Value
$600.4M
Shares
22.97M
% Port
29.19%
A
2.ADI

ANAPTYSBIO INC

Value
$531.9M
Shares
7.88M
% Port
25.86%
A

AKTIS ONCOLOGY INC

Value
$155.5M
Shares
4.82M
% Port
7.56%
C

CG ONCOLOGY INC

Value
$106.2M
Shares
1.49M
% Port
5.16%
E

ETON PHARMACEUTICALS INC

Value
$78.6M
Shares
2.17M
% Port
3.82%
C

CRISPR THERAPEUTICS AG

Value
$75.8M
Shares
1.39M
% Port
3.68%
O

ORIC PHARMACEUTICALS INC

Value
$72.9M
Shares
6.73M
% Port
3.54%
?
8.N/A

FIRST TRACKS BIOTHERAPEUTICS

Value
$63.9M
Shares
3.17M
% Port
3.11%
G

LAKEFRONT BIOTHERAPEUTICS NV

Value
$50M
Shares
1.67M
% Port
2.43%
N
10.NGNE

NEUROGENE INC

Value
$40M
Shares
1.27M
% Port
1.94%
C
11.CGON

CG ONCOLOGY INC

Value
$39.9M
Shares
561.5K
% Port
1.94%
S
12.STOK

STOKE THERAPEUTICS INC

Value
$24M
Shares
735.0K
% Port
1.17%
?
13.N/A

FULCRUM THERAPEUTICS INC

Value
$24M
Shares
6.55M
% Port
1.17%
L
14.LEGN

LEGEND BIOTECH CORP

Value
$23.1M
Shares
800.0K
% Port
1.12%
?
15.N/A

BRIDGEBIO ONCOLOGY THERAPEUT

Value
$21.5M
Shares
2.82M
% Port
1.05%
M
16.MBX

MBX BIOSCIENCES INC

Value
$21.4M
Shares
388.5K
% Port
1.04%
Z
17.ZBIO

ZENAS BIOPHARMA INC

Value
$20M
Shares
789.5K
% Port
0.97%
?
18.N/A

ATARA BIOTHERAPEUTICS INC

Value
$17.8M
Shares
1.55M
% Port
0.87%
R
19.RLAY

RELAY THERAPEUTICS INC

Value
$13.1M
Shares
697.9K
% Port
0.63%
A
20.AURA

AURA BIOSCIENCES INC

Value
$11.8M
Shares
1.67M
% Port
0.58%

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